Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23354423 | 0.98 | KDM5A (0.40) | KDM5AKDM4CKDM5BTSHRMGLL | |
| SCHEMBL2723759 | 0.81 | LCK (0.41) | KDM5AKDM4CKDM5BMGLLKDM4E | |
| SCHEMBL27745441 | 0.81 | KDM4E (0.47) | KDM5AKDM4CKDM5BKDM4EPTGER4 | |
| SCHEMBL1563562 | 0.80 | KDM5A (0.48) | KDM5AKDM4CKDM5BTSHRKDM4E | |
| SCHEMBL17324739 | 0.80 | KDM5A (0.42) | KDM5AKDM4CKDM5BTSHRMGLL | |
| SCHEMBL23354421 | 0.79 | KDM5A (0.43) | KDM5AKDM4CKDM5BTSHRKDM4E | |
| Methane SCHEMBL27733031 | 0.78 | KDM5A (0.47) | KDM5AKDM4CKDM5BMGLLKDM4E | |
| SCHEMBL3589934 | 0.78 | KDM5A (0.41) | KDM5AKDM4CKDM5BMGLLATM | |
| Hydrochloric Acid SCHEMBL29978648 | 0.76 | RAB9A (0.37) | KDM4EHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24405774 | 0.75 | KDM5A (0.39) | KDM5AKDM4CKDM5BMGLLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
| EP-3822268-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2021-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAM17 | KDM5A 2313/4885KDM4C 1947/4885KDM5B 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.