Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.58 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375950 | 0.89 | KLKB1 (0.54) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL4368099 | 0.87 | KLKB1 (0.51) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL4365940 | 0.86 | ITGB3 (0.58) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL27745374 | 0.85 | KLKB1 (0.64) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL4366047 | 0.85 | KLKB1 (0.53) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL4361537 | 0.85 | KLKB1 (0.59) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL4373683 | 0.84 | KLKB1 (0.54) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL4367194 | 0.84 | KLKB1 (0.54) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL27724715 | 0.84 | KLKB1 (0.57) | KLKB1USP30PPARGEPHX2PPARA | |
| SCHEMBL27724714 | 0.83 | USP30 (0.59) | KLKB1USP30PPARGEPHX2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101267813-A | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO CO LTD (JP) | 2008-09-17 | — | — | CN | disclosed |