Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.58 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368718 | 0.95 | ITGB3 (0.56) | ITGB3ITGA2BGPR132PPARGFPR2 | |
| SCHEMBL4368099 | 0.91 | KLKB1 (0.51) | ITGB3ITGA2BGPR132PPARGFPR2 | |
| SCHEMBL4375950 | 0.89 | KLKB1 (0.54) | ITGB3ITGA2BGPR132PPARGFPR2 | |
| SCHEMBL4366047 | 0.86 | KLKB1 (0.53) | ITGB3ITGA2BGPR132PPARGKLKB1 | |
| SCHEMBL27745461 | 0.86 | KLKB1 (0.58) | ITGB3ITGA2BGPR132PPARGKLKB1 | |
| SCHEMBL4368574 | 0.85 | KLKB1 (0.51) | ITGB3ITGA2BGPR132PPARGFPR2 | |
| SCHEMBL4374870 | 0.85 | KLKB1 (0.51) | ITGB3ITGA2BGPR132PPARGFPR2 | |
| SCHEMBL21931656 | 0.84 | CA2 (0.62) | ITGB3ITGA2BGPR132PPARGFPR2 | |
| SCHEMBL4361537 | 0.84 | KLKB1 (0.59) | ITGB3ITGA2BGPR132PPARGKLKB1 | |
| SCHEMBL12029248 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BGPR132PPARGKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344029-B2 | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20090292024-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| CN-101267813-A | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO CO LTD (JP) | 2008-09-17 | — | — | CN | disclosed |
| EP-1908466-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292024-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | PTMS, C1S, ACP3 | ITGB3 2667/4885ITGA2B 3988/4885GPR132 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.