Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054091 | 0.82 | HTR2C (0.54) | HTR2CHTR2AHTR2BBRD4ADRB2 | |
| SCHEMBL4096972 | 0.82 | HTR2C (0.54) | HTR2CHTR2AHTR2BBRD4ADRB2 | |
| SCHEMBL4107338 | 0.82 | HTR2C (0.54) | HTR2CHTR2AHTR2BBRD4ADRB2 | |
| SCHEMBL31389951 | 0.80 | AHR (0.43) | AHRHTR1ATRPV1HTR2CHTR2A | |
| SCHEMBL17429447 | 0.79 | HTR1A (0.51) | AHRHTR1ATRPV1HTR2CTRPA1 | |
| SCHEMBL13051078 | 0.74 | KDM1A (0.52) | MAPK1IDO1LMNA | |
| SCHEMBL28320141 | 0.73 | SLC6A4 (0.46) | AHRHTR1ATRPV1HTR2CHTR2A | |
| SCHEMBL14027792 | 0.73 | HTR1A (0.47) | AHRHTR1AHTR2CADRA1AMAP1LC3B | |
| SCHEMBL8995183 | 0.71 | HTR1A (0.48) | AHRHTR1AHTR2CADRA1AADRB1 | |
| SCHEMBL10676145 | 0.70 | HTR2C (0.63) | AHRHTR1AHTR2CADRA1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472890-A | 3- (1H-indol- 3-ydindan-1-ylamine derivatives for the treatment of depression and anxiety | LUNDBECK & CO AS H (DK) | 2009-07-01 | — | — | CN | disclosed |