Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425082 | 0.86 | EPHX1 (0.72) | EPHX1NPC1RAB9ARECQLEPHX2 | |
| Hydrochloric Acid SCHEMBL4601195 | 0.85 | EPHX1 (0.70) | EPHX1NPC1RAB9ARECQLEPHX2 | |
| Tert-Butyl Formate SCHEMBL28822399 | 0.83 | F10 (0.49) | EPHX2FAAHKMT2A | |
| Tert-Butyl Formate SCHEMBL27826415 | 0.83 | HTR6 (0.46) | EPHX1 | |
| Trifluoroacetic Acid SCHEMBL2953636 | 0.82 | EPHX1 (0.65) | EPHX1NPC1RAB9ARECQLEPHX2 | |
| SCHEMBL11417263 | 0.76 | RAB9A (0.84) | EPHX1NPC1RAB9ARECQLEPHX2 | |
| SCHEMBL11927282 | 0.76 | EPHX1 (0.63) | EPHX1NPC1RAB9AEPHX2MEN1 | |
| SCHEMBL14997509 | 0.76 | EPHX1 (0.72) | EPHX1NPC1RAB9AEPHX2MEN1 | |
| SCHEMBL12995588 | 0.76 | EPHX1 (0.63) | EPHX1NPC1RAB9AEPHX2MEN1 | |
| SCHEMBL14984059 | 0.75 | NPC1 (0.74) | EPHX1NPC1RAB9AEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326166-A | Novel N-sulfamoyl-piperidine amides for the prevention or treatment of obesity and related disorders | SOLVAY PHARM GMBH (DE) | 2008-12-17 | — | — | CN | disclosed |