Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Ethoxyethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethoxyethanol SCHEMBL5801442 | 0.94 | ALDH1A1 (0.88) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| 2-Ethoxyethanol SCHEMBL1123166 | 0.91 | — | — | |
| 2-Ethoxyethanol SCHEMBL337831 | 0.91 | — | — | |
| 2-Ethoxyethanol SCHEMBL11026181 | 0.91 | ALDH1A1 (0.93) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| 2-Ethoxyethanol SCHEMBL28220903 | 0.88 | — | — | |
| 2-Ethoxyethanol SCHEMBL10343650 | 0.88 | ALDH1A1 (0.88) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| 2-Ethoxyethanol SCHEMBL485434 | 0.88 | ALDH1A1 (0.88) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| 2-Ethoxyethanol SCHEMBL4686 | 0.88 | — | — | |
| 2-Ethoxyethanol SCHEMBL9432157 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| 2-Ethoxyethanol SCHEMBL9547497 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448818-C | Method for extracting and method for purifying effective substance | EZAKI GLICO CO (JP) | 2009-01-07 | — | — | CN | disclosed |
| CN-1589246-A | Method for extracting and method for purifying effective substance | EZAKI GLICO CO (JP) | 2005-03-02 | — | — | CN | disclosed |