Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840190 | 0.76 | MEN1 (0.66) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL17576480 | 0.76 | MEN1 (0.66) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL20735101 | 0.76 | MEN1 (0.62) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL30534976 | 0.75 | PRMT1 (0.68) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL9437170 | 0.75 | PRMT1 (0.68) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL3891083 | 0.75 | KMT2A (0.74) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL18588698 | 0.75 | MEN1 (0.64) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL30499259 | 0.75 | POLB (0.74) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL6887733 | 0.75 | ALDH1A1 (0.74) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL3773566 | 0.75 | POLB (0.74) | MEN1KMT2APOLBUSP2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101284827-B | Antineoplastic compounds containing triazole ring naphthoyl imines and method for preparing same | UNIV DALIAN TECH | 2010-12-08 | — | — | CN | disclosed |
| CN-101284827-A | Antineoplastic compounds containing triazole ring naphthoyl imines and method for preparing same | UNIV DALIAN TECH (CN) | 2008-10-15 | — | — | CN | disclosed |