Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.64 |
| ▸ | RGS12 | O14924 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3888669 | 0.94 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL11932614 | 0.94 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL17726925 | 0.91 | ALDH1A1 (0.78) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL6347785 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL30153490 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL22716950 | 0.85 | POLB (0.73) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL17576480 | 0.84 | MEN1 (0.66) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL19840190 | 0.84 | MEN1 (0.66) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL11629372 | 0.84 | KDM4E (0.70) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL6885854 | 0.83 | KDM4E (0.63) | ALDH1A1KDM4ELMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981804-B | Fast-response peroxynitrite fluorescent probe, preparation method and application | 山东省科学院生物研究所 | 2022-06-21 | — | — | CN | claimed |
| CN-110878085-B | Rapid high-selectivity hypobromous acid fluorescent probe, preparation method and application | 山东省科学院生物研究所 | 2020-11-13 | — | — | CN | claimed |
| CN-110878085-A | Rapid high-selectivity hypobromous acid fluorescent probe, preparation method and application | 山东省科学院生物研究所 | 2020-03-13 | — | — | CN | claimed |
| CN-118724857-A | Biochemical reagent for detecting mercapto of biological medicine and preparation method thereof | 中国医学科学院药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| CN-110981804-B | Fast-response peroxynitrite fluorescent probe, preparation method and application | 山东省科学院生物研究所 | 2022-06-21 | — | — | CN | disclosed |
| US-10851185-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2020-12-01 | — | — | US | disclosed |
| CN-110878085-B | Rapid high-selectivity hypobromous acid fluorescent probe, preparation method and application | 山东省科学院生物研究所 | 2020-11-13 | — | — | CN | disclosed |
| CN-110981804-A | Peroxynitrite fluorescent probe with rapid response, preparation method and application | 山东省科学院生物研究所 | 2020-04-10 | — | — | CN | disclosed |
| CN-110878085-A | Rapid high-selectivity hypobromous acid fluorescent probe, preparation method and application | 山东省科学院生物研究所 | 2020-03-13 | — | — | CN | disclosed |
| US-20190241680-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2019-08-08 | — | — | US | disclosed |
| US-20180079833-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2018-03-22 | — | — | US | disclosed |
| US-20090181927-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | PHOTOBIOMED CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-20090181927-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | PHOTOBIOMED CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| EP-2047866-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | PhotoBioMed Corporation (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7514399-B2 | Use in tissue bonding and protein cross-linking and use in tissue and arterial repair, preservation of expanded internal luminal diameters, and local delivery of drugs, skin care materials, sunscreens, and cosmetics | PHOTOBIOMED CORPORATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514399-B2 | Use in tissue bonding and protein cross-linking and use in tissue and arterial repair, preservation of expanded internal luminal diameters, and local delivery of drugs, skin care materials, sunscreens, and cosmetics | PHOTOBIOMED CORPORATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-6682938-B1 | USING COMPOUND HAVING SUBSTRATE-RECOGNITION COMPONENT, FLUORESCENCE ?SWITCH? MEDIATED BY SUBSTRATE RECOGNITION EVENT, AND FLUOROPHORE IN MOLECULE IN IMPLANTABLE SYSTEMS FOR CONTINUOUS TRANSDERMAL MONITORING OF BLOOD GLUCOSE LEVELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-01-27 | — | — | US | disclosed |
| US-6673625-B2 | NAPTHALIMIDE BORONATE DERIVATIVES AND SUBSTITUTED CHLOROBENZOPHENOXAZINONE BORONATE DERIVATIVES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-01-06 | — | — | US | disclosed |
| US-20020010279-A1 | Saccharide sensing molecules having enhanced fluorescent properties | LAWRENCE LIVERMORE NATIONAL SECURITY LLC | 2002-01-24 | — | — | US | disclosed |
| US-4814453-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181927-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, TAGLN2, DCLRE1A | ALDH1A1 1245/4885KDM4E 2778/4885LMNA 436/4885 |
| US-20020010279-A1 | Saccharide sensing molecules having enhanced fluorescent properties | SLC2A1, SLC2A9, SLC2A2 | ALDH1A1 261/4885KDM4E 3240/4885LMNA 1541/4885 |
| US-20180079833-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, BMP2, TAGLN2 | ALDH1A1 1539/4885KDM4E 2772/4885LMNA 385/4885 |
| US-10851185-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | BMP2, SUN2, TAGLN2 | ALDH1A1 1456/4885KDM4E 2869/4885LMNA 383/4885 |
| US-20190241680-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | BMP2, SUN2, TAGLN2 | ALDH1A1 1456/4885KDM4E 2869/4885LMNA 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.