Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27746239

CC(C)C1c2ccccc2-c2ccc(-c3ccccc3)c(-c3ccccc3)c21.N

nearest known ligand 0.35

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
GCGR P47871 1/20 0.33
MAOB P27338 4/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
ADRA2A P08913 5/20 0.31
ADRA2B P18089 5/20 0.31
ADRA2C P18825 5/20 0.31
MAOA P21397 3/20 0.31
NISCH Q9Y2I1 1/20 0.31
GPR3 P46089 1/20 0.31
BRD4 O60885 1/20 0.31
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28120033 0.81 ALDH1A1 (0.33) MEN1POLBKMT2AATMCYP1A2
SCHEMBL27659967 0.73 HDAC4 (0.40) MEN1KMT2ACHRNB2CHRNA4HTR7
SCHEMBL28107581 0.73 ALDH1A1 (0.36) CYP1A2CHRNB2CHRNA4ADRA2AADRA2B
SCHEMBL3919889 0.73 GPR3 (0.46) MEN1POLBKMT2AATMCYP1A2
Ammonia Solution, Strong SCHEMBL27746302 0.71 HTR2A (0.37) CHRNB2CHRNA4
SCHEMBL17024335 0.70 DPP4 (0.37) MEN1POLBKMT2AATMCYP1A2
SCHEMBL28980164 0.69 KMT2A (0.35) MEN1POLBKMT2AATMCHRNB2
Ammonia Solution, Strong SCHEMBL27746261 0.69 IDO1 (0.38) MEN1KMT2ACHRNB2CHRNA4
SCHEMBL24808036 0.68 FABP3 (0.37) MEN1POLBKMT2AATMCYP1A2
SCHEMBL6629142 0.67 CDC25A (0.39) MEN1POLBKMT2AATMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101904028-A organic electroluminescent element IDEMITSU KOSAN CO 2010-12-01 CN disclosed
CN-101473464-A Organic electroluminescent element using heterocyclic aromatic amine derivative IDEMITSU KOSAN CO (JP) 2009-07-01 CN disclosed