Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643582 | 0.83 | MAPT (0.40) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2644689 | 0.82 | MAPT (0.43) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2664954 | 0.81 | CASP3 (0.39) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2664915 | 0.81 | CASP3 (0.39) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2644694 | 0.81 | MAPT (0.39) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL15926258 | 0.74 | MAPT (0.36) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2644105 | 0.74 | MAPT (0.46) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2644875 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1MAPTKDM4ELMNAL3MBTL1 | |
| SCHEMBL2644355 | 0.73 | PARP1 (0.37) | ALDH1A1MAPTKDM4EATMTSHR | |
| SCHEMBL2643618 | 0.73 | MAPT (0.40) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316836-A | Substituted dihydroisoindolones as allosteric modulators of glucokinase | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-03 | — | — | CN | disclosed |