⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433889 | 0.72 | — | — | |
| SCHEMBL63023 | 0.72 | — | — | |
| SCHEMBL29483856 | 0.72 | — | — | |
| SCHEMBL30386373 | 0.72 | — | — | |
| SCHEMBL18171776 | 0.72 | GABRA1 (0.41) | — | |
| Fluoride SCHEMBL27460684 | 0.70 | — | — | |
| SCHEMBL14404281 | 0.69 | — | — | |
| SCHEMBL416458 | 0.68 | — | — | |
| SCHEMBL1638197 | 0.68 | — | — | |
| SCHEMBL13220496 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028365-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12528784-B2 | Alkynyl-(heteroaryl)-carboxamide HCN1 inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250325544-A1 | CDK INHIBITORS | GENENTECH, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250281487-A1 | CDK INHIBITORS | GENENTECH, INC. (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250275972-A1 | CDK INHIBITORS | GENENTECH, INC. (US) | 2025-09-04 | — | — | US | disclosed |
| US-20250275971-A1 | CDK INHIBITORS | GENENTECH, INC. (US) | 2025-09-04 | — | — | US | disclosed |
| CN-120040446-A | CDK inhibitors | 基因泰克公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4554938-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| US-12285429-B2 | CDK inhibitors | GENENTECH, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
| EP-1654251-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008087057-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2008-07-24 | — | — | WO | disclosed |
| US-20060205740-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2006-09-14 | — | — | US | disclosed |
| EP-1654251-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005092899-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005016914-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| US-6417187-B2 | PALLADIUM CATALYZED ARYLATION, ALKYLATION, DEIODINATION OR DEBROMINATION | DOW AGROSCIENCES LLC | 2002-07-09 | — | — | US | disclosed |
| US-20020019370-A1 | Palladium catalyzed arylation, alkylation, deiodination or debromination | DOW AGROSCIENCES LLC | 2002-02-14 | — | — | US | disclosed |