Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3644542 | 0.79 | HTR6 (1.00) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL14451017 | 0.75 | HTR6 (0.85) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL5349372 | 0.75 | HTR6 (0.65) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL10325495 | 0.75 | KDM4E (0.50) | L3MBTL1HTR7 | |
| SCHEMBL20564256 | 0.74 | HTR6 (0.72) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL1997547 | 0.74 | HTR6 (0.63) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL28788060 | 0.73 | HTR6 (0.62) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL724446 | 0.72 | HTR6 (0.65) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL5358790 | 0.72 | HTR6 (0.65) | HTR6CA12CA9CA2CA1 | |
| SCHEMBL29728504 | 0.72 | HTR6 (0.65) | HTR6CA12CA9CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |