SCHEMBL20564256

SCHEMBL20564256

O=S(=O)(c1ccccc1)n1cc(-c2ccsc2)c2ccccc21

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 14/20 0.72
CA12 O43570 3/20 0.62
CA9 Q16790 3/20 0.62
CA2 P00918 2/20 0.62
CA1 P00915 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.60
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
DRD2 P14416 3/20 0.51
HTR2A P28223 2/20 0.49
HTR7 P34969 2/20 0.49
HTR1A P08908 1/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20561500 0.90 L3MBTL1 (0.73) HTR6CA12CA9CA2CA1
SCHEMBL20562314 0.87 HTR6 (0.54) HTR6CA12CA9CA2CA1
SCHEMBL3644542 0.84 HTR6 (1.00) HTR6CA12CA9CA2CA1
SCHEMBL7990679 0.79 L3MBTL1 (0.60) HTR6CA12CA9CA2CA1
SCHEMBL1413630 0.78 CXCR4 (0.48) HTR6CA12CA9CA2CA1
SCHEMBL14451017 0.77 HTR6 (0.85) HTR6CA12CA9CA2CA1
SCHEMBL5358790 0.77 HTR6 (0.65) HTR6CA12CA9CA2CA1
SCHEMBL1651879 0.75 HTR6 (0.74) HTR6CA12CA9CA2CA1
SCHEMBL21959033 0.75 HTR6 (0.74) HTR6CA12CA9CA2CA1
SCHEMBL7497252 0.75 HTR6 (0.74) HTR6CA12CA9CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018210661-A1 HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES BASF SE (DE) 2018-11-22 WO disclosed
WO-2018210660-A1 HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES BASF SE (DE) 2018-11-22 WO disclosed
WO-2018210658-A1 HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES BASF SE (DE) 2018-11-22 WO disclosed
WO-2018210659-A1 HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES BASF SE (DE) 2018-11-22 WO disclosed