SCHEMBL27747237

SCHEMBL27747237

C=CC(=O)NS(=O)(=O)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
TGM2 P21980 3/20 0.33
F13A1 P00488 1/20 0.33
TGM1 P22735 1/20 0.33
PSMB11 A5LHX3 1/20 0.31
PSMA7 O14818 1/20 0.31
PSMB1 P20618 1/20 0.31
PSMA1 P25786 1/20 0.31
PSMA2 P25787 1/20 0.31
PSMA3 P25788 1/20 0.31
PSMA4 P25789 1/20 0.31
PSMB8 P28062 1/20 0.31
PSMB9 P28065 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687517 0.85 ZDHHC20 (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27495616 0.83 ZDHHC20 (0.37) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL1068444 0.82 HPGD (0.46) TSHRZDHHC20ZDHHC2CA1CA2
SCHEMBL28575047 0.81 ALDH1A1 (0.34) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28756092 0.80 ZDHHC20 (0.46) ZDHHC20ZDHHC2CA1CA2
SCHEMBL1670876 0.79 TSHR (0.44) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27511296 0.79 ZDHHC20 (0.49) TSHRMAPK1ZDHHC20ZDHHC2CA1
SCHEMBL27694934 0.79 ZDHHC20 (0.49) TSHRMAPK1ZDHHC20ZDHHC2CA1
SCHEMBL27676445 0.79 ZDHHC20 (0.49) TSHRMAPK1ZDHHC20ZDHHC2CA1
SCHEMBL28135574 0.79 ZDHHC20 (0.49) TSHRMAPK1ZDHHC20ZDHHC2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102348747-B Binders for coatings, having high water vapor permeability BASF SE 2013-08-14 CN claimed
CN-102348747-A Binders for coatings, having high water vapor permeability BASF SE 2012-02-08 CN claimed
CN-107920970-A Cosmetic composition comprising salicylic acid compound 莱雅公司 2018-04-17 CN disclosed
CN-107787214-A Oil in water emulsion composition 莱雅公司 2018-03-09 CN disclosed
CN-107714498-A Include the cosmetic composition of cucurbit acid compound 莱雅公司 2018-02-23 CN disclosed
CN-107095796-A Dye composite for dyeing keratin fibres 莱雅公司 2017-08-29 CN disclosed
CN-107106435-A Cosmetics flushing type skin care compositions and methods and use its cosmetic method 莱雅公司 2017-08-29 CN disclosed
CN-106459652-A Functionalised copolymers and the use thereof as binding agent for coatings 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-105658199-A Cosmetic composition comprising sulphonic polymer, hydrophobic polysaccharide and silicone surfactant 莱雅公司 2016-06-08 CN disclosed
CN-105377222-A Dye composition comprising a particular amphoteric surfactant and a particular thickening polymer L'OREAL S A 2016-03-02 CN disclosed
CN-103442686-A Sunscreening emulsion containing two specific amphiphilic copolymers and at least a lipophilic organic UV filter OREAL 2013-12-11 CN disclosed
CN-102471421-B Aqueous polymer dispersions and their use as adhesives for coating substrates BASF SE 2013-11-13 CN disclosed
CN-103379896-A Composition for dyeing keratin fibres comprising a direct dye bearing a disulfide/thiol function, a nonionic surfactant, an amphoteric surfactant, an ethoxylated fatty alcohol, an alkaline agent and a reducing agent OREAL 2013-10-30 CN disclosed
CN-103370046-A Composition for dyeing keratin fibres comprising a direct dye having a disulfide/thiol function, a non-cellulose-based thickening polymer, an alkaline agent and a reducing agent OREAL 2013-10-23 CN disclosed
CN-102348747-B Binders for coatings, having high water vapor permeability BASF SE 2013-08-14 CN disclosed
CN-102471421-A Aqueous polymer dispersions and their use as adhesives for coating substrates BASF SE 2012-05-23 CN disclosed
CN-102348747-A Binders for coatings, having high water vapor permeability BASF SE 2012-02-08 CN disclosed
CN-102046282-A Polymer foams BASF SE 2011-05-04 CN disclosed
CN-101484128-A Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use OREAL (FR) 2009-07-15 CN disclosed