Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407233 | 0.86 | KCNJ1 (0.47) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28938445 | 0.86 | KCNJ1 (0.47) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL14424184 | 0.81 | KCNJ1 (0.46) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10854988 | 0.79 | KCNJ1 (0.49) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL173199 | 0.77 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16806060 | 0.77 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16806066 | 0.77 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1966503 | 0.75 | KCNJ1 (0.44) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9805956 | 0.75 | KCNJ1 (0.49) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6554242 | 0.75 | ALDH1A1 (0.53) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101481359-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-07-15 | — | — | CN | claimed |