Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806060 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL16806066 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL21660622 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL6558724 | 0.90 | HSPB1 (0.53) | ALDH1A1KCNJ1KCNH2MAPTMAPK1 | |
| SCHEMBL19788211 | 0.85 | KCNJ1 (0.48) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL10854988 | 0.82 | KCNJ1 (0.49) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL16806400 | 0.82 | KCNJ1 (0.49) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL9805956 | 0.82 | KCNJ1 (0.49) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL6554242 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 | |
| SCHEMBL6554390 | 0.82 | LOXL2 (0.52) | ALDH1A1KCNJ1KCNH2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191752-B2 | Compounds and methods of treating retinal degeneration | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-12-07 | — | — | US | disclosed |
| US-10934303-B2 | Aryl ethene derivative and pharmaceutical composition containing same as active ingredient | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-03-02 | — | — | US | disclosed |
| US-20200230119-A1 | COMPOUNDS AND METHODS OF TREATING RETINAL DEGENERATION | CASE WESTERN RESERVE UNIVERSITY | 2020-07-23 | — | — | US | disclosed |
| CN-106995374-B | Method for preparing nitroaromatic acid/nitro alpha-aryl alcohol by oxidizing substituted alkyl nitrobenzene with oxygen | 浙江工业大学 | 2019-11-29 | — | — | CN | disclosed |
| US-20190161490-A1 | NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | NOVMETAPHARMA CO., LTD. (KR) | 2019-05-30 | — | — | US | disclosed |
| US-20180162847-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2018-06-14 | — | — | US | disclosed |
| US-9982068-B2 | Redox active polymers and colloidal particles for flow batteries | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-05-29 | — | — | US | disclosed |
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-03-08 | — | — | US | disclosed |
| US-9872911-B2 | Alpha-aminoamidine polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9785011-B2 | Liquid crystal display having improved wavelength dispersion characteristics | AKRON POLYMER SYSTEMS (US) | 2017-10-10 | — | — | US | disclosed |
| US-20080241427-A1 | Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides | AKRON POLYMER SYSTEMS | 2008-10-02 | — | — | US | disclosed |
| US-20080241428-A1 | Optical compensation films with disk groups for liquid crystal display | AKRON POLYMER SYSTEMS | 2008-10-02 | — | — | US | disclosed |
| US-20080239491-A1 | Optical compensation films having positive birefringence for liquid crystal display | AKRON POLYMER SYSTEMS | 2008-10-02 | — | — | US | disclosed |
| US-20080241745-A1 | Mixture of alkali soluble polymer, crosslinking agent, acid generator ; radiation with actinic radiation; quaternary ammonium compound | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| WO-2007064861-A2 | ASYMMETRIC FRIEDEL-CRAFTS ALKYLATIONS CATALYZED BY BYFUNCTIONAL CINCHONA ALKALOIDS | BRANDEIS UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5711020-A | BIODEGRADATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ENVIRONMENTAL PROTECTION AGENCY (US) | 1998-01-20 | — | — | US | disclosed |
| US-3947434-A | 9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200230119-A1 | COMPOUNDS AND METHODS OF TREATING RETINAL DEGENERATION | PDE6A, PDE6H, PDE6D | ALDH1A1 1072/4885KCNJ1 2293/4885KCNH2 1922/4885 |
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | CCNO, PTGDR, CCNE1 | ALDH1A1 2970/4885KCNJ1 4321/4885KCNH2 2769/4885 |
| US-20190161490-A1 | NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | ESRRG, ESR2, ESR1 | ALDH1A1 262/4885KCNJ1 2751/4885KCNH2 3525/4885 |
| US-11191752-B2 | Compounds and methods of treating retinal degeneration | PDE6A, PDE6H, PDE6D | ALDH1A1 1072/4885KCNJ1 2293/4885KCNH2 1922/4885 |
| US-20180162847-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | PRMT5, PRMT1, PRMT3 | ALDH1A1 2705/4885KCNJ1 3843/4885KCNH2 4127/4885 |
| US-10934303-B2 | Aryl ethene derivative and pharmaceutical composition containing same as active ingredient | ESRRG, ESR1, ESR2 | ALDH1A1 263/4885KCNJ1 2965/4885KCNH2 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.