Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 8/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774155 | 0.86 | SLC6A4 (0.56) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL2775297 | 0.83 | CHRM5 (0.56) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL2775792 | 0.81 | CHRM5 (0.52) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL2773429 | 0.78 | CHRM5 (0.61) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL3950616 | 0.78 | CHRM5 (0.61) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL3949670 | 0.78 | CHRM5 (0.61) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL2774716 | 0.78 | CHRM5 (0.61) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL2776390 | 0.77 | SLC6A4 (0.54) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL5918305 | 0.77 | SLC6A4 (0.58) | CHRM5CHRM1SLC6A4CHRM4CHRM3 | |
| SCHEMBL2776295 | 0.76 | HTR1A (0.38) | SLC6A4CHRM4DRD2HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112488-A1 | METHOD FOR OBTAINING 1,3-DIFUNCTIONALIZED PYRROLIDINE DERIVATIVES | RAGACTIVES, S.L.U. (ES) | 2010-10-07 | — | — | WO | claimed |
| EP-2236509-A1 | Method for obtaining 1,3-difunctionalized pyrrolidine derivatives | Ragactives, S.L. (ES) | 2010-10-06 | — | — | EP | claimed |
| WO-2010112488-A1 | METHOD FOR OBTAINING 1,3-DIFUNCTIONALIZED PYRROLIDINE DERIVATIVES | RAGACTIVES, S.L.U. (ES) | 2010-10-07 | — | — | WO | disclosed |
| EP-2236509-A1 | Method for obtaining 1,3-difunctionalized pyrrolidine derivatives | Ragactives, S.L. (ES) | 2010-10-06 | — | — | EP | disclosed |