Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747739 | 1.00 | AR (0.38) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL27747683 | 0.84 | CHRNB2 (0.36) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL27768798 | 0.84 | CHRNB2 (0.36) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL27747688 | 0.84 | AR (0.36) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL27768769 | 0.84 | AR (0.36) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL17504401 | 0.81 | CHRNB2 (0.38) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL17504400 | 0.81 | CHRNB2 (0.38) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL17504399 | 0.81 | CHRNB2 (0.38) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL12057414 | 0.81 | AR (0.52) | ARCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL30716841 | 0.80 | AR (0.40) | ARCA1CA2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466679-A | Process for preparing tetrahydroquinoline derivatives | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-06-24 | — | — | CN | claimed |
| CN-101466679-A | Process for preparing tetrahydroquinoline derivatives | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-06-24 | — | — | CN | disclosed |