Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747683 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL27768769 | 0.86 | AR (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL27747688 | 0.86 | AR (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL27747677 | 0.84 | AR (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL27747739 | 0.84 | AR (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL12057414 | 0.76 | AR (0.52) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL30716841 | 0.75 | AR (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL29740491 | 0.75 | AR (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL17504397 | 0.75 | AR (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3AR | |
| SCHEMBL26989692 | 0.75 | AR (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466679-A | Process for preparing tetrahydroquinoline derivatives | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-06-24 | — | — | CN | disclosed |