Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071793 | 0.88 | KDM4E (0.51) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL7670560 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL21822426 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL1072812 | 0.84 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL1074230 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL27592569 | 0.83 | CA12 (0.53) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL1071765 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL1071701 | 0.80 | MTNR1A (0.49) | KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL21585555 | 0.80 | NR4A1 (0.53) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL15936293 | 0.79 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421249-A | 4,5-diphenyl-pyrimidinyl-oxy or -mercapto substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND (FR) | 2009-04-29 | — | — | CN | disclosed |