Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747384 | 0.73 | TSHR (0.36) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL3047206 | 0.73 | — | — | |
| SCHEMBL28591035 | 0.70 | — | — | |
| SCHEMBL602183 | 0.70 | — | — | |
| SCHEMBL600731 | 0.70 | — | — | |
| SCHEMBL600730 | 0.70 | — | — | |
| SCHEMBL9655412 | 0.70 | — | — | |
| SCHEMBL5820855 | 0.69 | — | — | |
| SCHEMBL10012423 | 0.68 | CYP2C19 (0.65) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL606619 | 0.68 | ALDH1A1 (0.64) | TSHRALDH1A1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101412667-B | Preparation of 2-pimelie kelone compound | UNIV ZHEJIANG TECHNOLOGY | 2012-06-27 | — | — | CN | disclosed |
| CN-101412667-A | Preparation of 2-pimelie kelone compound | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-04-22 | — | — | CN | disclosed |