Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880887 | 0.89 | PTGS2 (0.64) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL2886958 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL15267399 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL2889216 | 0.80 | TTR (0.57) | PTGS2PTGS1ABCB11NR1I3CAMK2A | |
| SCHEMBL14307499 | 0.74 | PTGS2 (0.63) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL13688513 | 0.72 | PTGS2 (0.66) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL2888394 | 0.72 | PTGS2 (0.60) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL21401012 | 0.72 | TTR (0.57) | PTGS2PTGS1ABCB11NR1I3CAMK2A | |
| SCHEMBL15267404 | 0.71 | PTGS2 (0.62) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL2881532 | 0.71 | TTR (0.59) | PTGS2PTGS1ABCB11NR1I3CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101501018-A | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC (CA) | 2009-08-05 | — | — | CN | disclosed |
| CN-101490029-A | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC (CA) | 2009-07-22 | — | — | CN | disclosed |