Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748011 | 0.91 | MAPK8 (0.41) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10455395 | 0.69 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4649729 | 0.68 | DPP4 (0.40) | HPGDALDH1A1SMN1; SMN2MAPTMAPK8 | |
| SCHEMBL8203711 | 0.68 | ALDH1A1 (0.53) | ALDH1A1MAPTMRGPRX4ADRB2ADRB1 | |
| SCHEMBL10575617 | 0.66 | MAPT (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2819868 | 0.66 | MAPT (0.55) | ALDH1A1MAPTMRGPRX4ADRB2ADRB1 | |
| SCHEMBL4762265 | 0.65 | ALDH1A1 (0.56) | ALDH1A1MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL27481339 | 0.65 | MAPT (0.47) | ALDH1A1MAPTMRGPRX4ADRB2ADRB1 | |
| SCHEMBL28649657 | 0.64 | ALDH1A1 (0.54) | ALDH1A1MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL27100548 | 0.64 | MAPT (0.56) | ALDH1A1SMN1; SMN2MAPTMAPK1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346648-B | Photochromic materials with electron-withdrawing substituents | TRANSITIONS OPTICAL INC | 2011-07-06 | — | — | CN | disclosed |
| CN-101346648-A | Photochromic materials with electron-withdrawing substituents | TRANSITIONS OPTICAL INC (US) | 2009-01-14 | — | — | CN | disclosed |