Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748011 | 0.79 | MAPK8 (0.41) | HPGDPRNPPPARGRXFP1NR2E3 | |
| SCHEMBL3143388 | 0.71 | PRNP (0.39) | DPP4HPGDPRNPPPARGRXFP1 | |
| SCHEMBL19834746 | 0.70 | TRPA1 (0.42) | MEN1KMT2ALMNAACE2 | |
| SCHEMBL824275 | 0.69 | ALDH1A1 (0.48) | DPP4PRNPPPARGRXFP1NR2E3 | |
| SCHEMBL4584724 | 0.69 | ALDH1A1 (0.48) | DPP4PRNPPPARGRXFP1NR2E3 | |
| SCHEMBL27748010 | 0.68 | NPC1 (0.38) | HPGDALDH1A1MAPTGAAMAPK8 | |
| SCHEMBL30136959 | 0.68 | ALDH1A1 (0.46) | DPP4PRNPPPARGRXFP1NR2E3 | |
| SCHEMBL389776 | 0.68 | ALDH1A1 (0.46) | DPP4PRNPPPARGRXFP1NR2E3 | |
| SCHEMBL13777187 | 0.68 | DCLK1 (0.50) | DPP4PRNPPPARGRXFP1NR2E3 | |
| SCHEMBL4572765 | 0.66 | ALDH1A1 (0.44) | DPP4PRNPPPARGRXFP1NR2E3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963896-A1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL, INC. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007073462-A1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL, INC. (US) | 2007-06-28 | — | — | WO | disclosed |