Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | HPGD | P15428 | 4/20 | 0.79 |
| ▸ | GLA | P06280 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | ACHE | P22303 | 2/20 | 0.79 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL29200445 | 0.92 | MAPT (0.83) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL27603600 | 0.92 | ALDH1A1 (0.94) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL7933049 | 0.89 | ALDH1A1 (0.62) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL4972293 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL3045498 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL8339 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL1772714 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL29352289 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL618814 | 0.86 | ALDH1A1 (0.94) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL10801271 | 0.86 | ALDH1A1 (0.94) | ALDH1A1HPGDGLAMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957085-A | Synthetic method and application of polycyano-substituted indole heterocyclic compound | 华南师范大学 | 2022-08-30 | — | — | CN | claimed |
| CN-107090190-B | A kind of acridine salt dyestuff and its preparation method and application | 北京科技大学 | 2019-09-06 | — | — | CN | claimed |
| CN-107090190-A | One class acridine salt dyestuff and its preparation method and application | 北京科技大学 | 2017-08-25 | — | — | CN | claimed |
| CN-101495596-A | Electroluminescent device | MERCK PATENT GMBH (DE) | 2009-07-29 | — | — | CN | claimed |
| CN-114957085-B | Synthetic method and application of polycyano substituted indole heterocyclic compound | 华南师范大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-114957085-A | Synthetic method and application of polycyano-substituted indole heterocyclic compound | 华南师范大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-107090190-B | A kind of acridine salt dyestuff and its preparation method and application | 北京科技大学 | 2019-09-06 | — | — | CN | disclosed |
| CN-107090190-A | One class acridine salt dyestuff and its preparation method and application | 北京科技大学 | 2017-08-25 | — | — | CN | disclosed |
| CN-101495596-A | Electroluminescent device | MERCK PATENT GMBH (DE) | 2009-07-29 | — | — | CN | disclosed |