SCHEMBL7933049

SCHEMBL7933049

c1ccc(-c2ccc3nc4ccccc4cc3c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
GLA P06280 2/20 0.62
HPGD P15428 2/20 0.62
MAPT P10636 1/20 0.62
ACHE P22303 1/20 0.62
BACE1 P56817 3/20 0.61
PDE10A Q9Y233 1/20 0.53
NPC1 O15118 2/20 0.50
POLB P06746 2/20 0.50
RAB9A P51151 2/20 0.50
HTR3A P46098 1/20 0.47
PIK3CA P42336 3/20 0.46
PIK3CD O00329 2/20 0.46
PIK3CB P42338 1/20 0.46
MTOR P42345 1/20 0.46
PIK3CG P48736 1/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
PTBP1 P26599 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28201590 0.94 BACE1 (0.62) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL9712227 0.94 ALDH1A1 (0.71) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL24184582 0.93 BACE1 (0.54) ALDH1A1GLAHPGDMAPTACHE
Acridine SCHEMBL27748113 0.89 ALDH1A1 (0.79) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL24184419 0.88 MEN1 (0.53) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL20121223 0.88 MAPT (0.62) ALDH1A1GLAHPGDMAPTACHE
Acridine SCHEMBL29200445 0.87 MAPT (0.83) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL27956641 0.86 MAPT (0.56) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL28592037 0.85 ALDH1A1 (0.54) ALDH1A1GLAHPGDMAPTACHE
SCHEMBL28819755 0.83 SRC (0.55) ALDH1A1GLAHPGDMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114351150-A Corrosion inhibitor and preparation method and application thereof 广东红日星实业有限公司 2022-04-15 CN claimed
CN-117143018-A Synthesis method of rare earth catalytic nitrogen-containing heterocyclic compound 温州大学新材料与产业技术研究院 2023-12-01 CN disclosed
CN-114351150-A Corrosion inhibitor and preparation method and application thereof 广东红日星实业有限公司 2022-04-15 CN disclosed
CN-114351150-A Corrosion inhibitor and preparation method and application thereof 广东红日星实业有限公司 2022-04-15 CN disclosed
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed