Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 9/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318767 | 1.00 | P2RX3 (0.46) | P2RX3P2RX2CYP2C9HDAC4MAP4K4 | |
| SCHEMBL4324205 | 0.91 | P2RX3 (0.45) | P2RX3P2RX2CYP2C9 | |
| SCHEMBL4322514 | 0.91 | P2RX3 (0.57) | P2RX3P2RX2CYP2C9 | |
| SCHEMBL27769417 | 0.91 | P2RX3 (0.57) | P2RX3P2RX2CYP2C9 | |
| SCHEMBL2278031 | 0.89 | P2RX3 (0.48) | P2RX3P2RX2CYP2C9HDAC4MAP4K4 | |
| SCHEMBL28790992 | 0.89 | P2RX3 (0.48) | P2RX3P2RX2CYP2C9HDAC4MAP4K4 | |
| SCHEMBL11990755 | 0.88 | P2RX3 (0.51) | P2RX3P2RX2MAP4K4 | |
| SCHEMBL357102 | 0.87 | P2RX3 (0.48) | P2RX3P2RX2MAP4K4AHR | |
| SCHEMBL10244154 | 0.86 | P2RX3 (0.53) | P2RX3P2RX2MAP4K4 | |
| SCHEMBL4327153 | 0.86 | P2RX3 (0.53) | P2RX3P2RX2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479250-A | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |