SCHEMBL277483

SCHEMBL277483

CNC(=O)/C=C\C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178479 1.00
SCHEMBL2166225 1.00
SCHEMBL1630764 0.87 CHRNB2 (0.44)
SCHEMBL2486077 0.87 CHRNB2 (0.44)
SCHEMBL1630761 0.87 CHRNB2 (0.44)
SCHEMBL3261026 0.83 TSHR (0.40)
Fumaric Acid SCHEMBL9689356 0.81 TSHR (0.60)
Fumaric Acid SCHEMBL9549887 0.81 TSHR (0.60)
Fumaric Acid SCHEMBL5875198 0.81 TSHR (0.69)
Maleic Acid SCHEMBL5875187 0.81 TSHR (0.69)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974451-B Efficient environment-friendly water reducer and preparation method thereof 甘肃金凯宁工贸集团有限公司 2024-02-20 CN claimed
CN-115974451-A Novel efficient environment-friendly water reducing agent and preparation method thereof 甘肃金凯宁工贸集团有限公司 2023-04-18 CN claimed
CN-112898623-B Liquid phase gel for temperature and pH coupling response type gel foam, preparation method, gel foam, preparation method and application thereof 中国石油大学(华东) 2023-01-24 CN claimed
EP-0495834-B1 METHOD FOR PREPARING IMIDE-CONTAINING POLYMERS DOW CHEMICAL CO (US) 1995-09-27 EP claimed
EP-0403240-B1 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS (JP) 1994-08-24 EP claimed
EP-0372922-B1 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS (JP) 1994-03-09 EP claimed
US-5175309-A Forming an imide by heat catalytic dehydration MITSUI TOATSU CHEMICALS INC. (JP) 1992-12-29 US claimed
EP-0495834-A4 METHOD FOR PREPARING IMIDE-CONTAINING POLYMERS 1992-08-26 EP claimed
EP-0495834-A1 METHOD FOR PREPARING IMIDE-CONTAINING POLYMERS. DOW CHEMICAL CO (US) 1992-07-29 EP claimed
US-5068357-A Heat dehydration of an N-substituted maleamic acid with a solvent, distillation after imidation, in the presence of a tin catalyst MITSUI TOATSU CHEMICALS, INC. (JP) 1991-11-26 US claimed
US-5015712-A Method for preparing imide-containing polymers THE DOW CHEMICAL COMPANY (US) 1991-05-14 US claimed
WO-1991005812-A1 METHOD FOR PREPARING IMIDE-CONTAINING POLYMERS THE DOW CHEMICAL COMPANY (US) 1991-05-02 WO claimed
EP-0403240-A1 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-12-19 EP claimed
EP-0372922-A2 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-13 EP claimed
JP-61053306-A None JP disclosed
EP-4727545-A2 COMBINATION TREATMENTS FOR DEPRESSION AND OTHER DISORDERS Neurawell Therapeutics (US) 2026-04-22 EP disclosed
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF Sea Pharmaceuticals LLC. (US) 2025-03-06 US disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed
EP-0121974-A1 Polymer mixture comprising a polyphenylene ether and optionally a polystyrene and/or a rubber-modified polystyrene, and articles formed therefrom GENERAL ELECTRIC COMPANY (US) 1984-10-17 EP disclosed
US-4154707-A VINYLENEDICARBONYL COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-05-15 US disclosed