SCHEMBL2486077

SCHEMBL2486077

CNC(=O)/C=C\C(=O)NC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA4 P43681 1/20 0.44
PARP1 P09874 2/20 0.39
PARP10 Q53GL7 2/20 0.39
PARP14 Q460N5 1/20 0.39
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
HCAR2 Q8TDS4 2/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
PELI1 Q96FA3 3/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 2/20 0.32
NMT1 P30419 1/20 0.30
PLAU P00749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1630764 1.00 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4PARP1
SCHEMBL1630761 1.00 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4PARP1
SCHEMBL277483 0.87
SCHEMBL15449450 0.87
SCHEMBL2166225 0.87
SCHEMBL178479 0.87
SCHEMBL5175963 0.85
SCHEMBL381340 0.85
SCHEMBL22820901 0.85 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4PARP1
SCHEMBL3706453 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3957732-A ALTERNATING COPOLYMERS HAVING FUNCTIONAL GROUP AND PROCESS FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-18 US claimed
EP-3983462-B1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2025-01-08 EP disclosed
US-20220306791-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2022-09-29 US disclosed
US-11427728-B2 Method for producing aqueous dispersions BASF SE (DE) 2022-08-30 US disclosed
EP-3983462-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2022-04-20 EP disclosed
US-11292861-B2 Aqueous polymer dispersion BASF SE (DE) 2022-04-05 US disclosed
US-20210292457-A1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2021-09-23 US disclosed
US-10916779-B2 Dispersant for resin collectors, material for resin collectors, and resin collector SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-02-09 US disclosed
WO-2020249706-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2020-12-17 WO disclosed
EP-3523382-B1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS BASF SE (DE) 2020-11-18 EP disclosed
EP-2379603-A1 BINDER COMPOSITIONS COMPRISING BORIC ACID OR BORIC ACID SALT BASF SE (DE) 2011-10-26 EP disclosed
US-20110257302-A1 BINDER COMPOSITIONS COMPRISING BORIC ACID OR BORIC ACID SALT BASF SE (DE) 2011-10-20 US disclosed
WO-2010072697-A1 BINDER COMPOSITIONS COMPRISING BORIC ACID OR BORIC ACID SALT BASF SE (DE) 2010-07-01 WO disclosed
US-7579320-B2 IAP BIR domain binding compounds AEGERA THERAPEUTICS, INC. 2009-08-25 US disclosed
US-20080069812-A1 Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents AEGERA THERAPEUTICS, INC. (CA) 2008-03-20 US disclosed
US-6315926-B1 HAZE-FREE DSM N.V. (NL) 2001-11-13 US disclosed
US-6068967-A IN WHICH ONLY A DESIRED HYDROPHILIC COLLOID LAYER IS SELECTIVELY COLORED. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
US-4190687-A WITH COPOLYMER OF ETHYLENEICALLY UNSATURATED ESTER AND ETHYLENICALLY UNSATURATED HYDROCARBON TO PREVENT COLOR BLEEDING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-02-26 US disclosed
US-3964955-A Bonding method using olefin-acrylic ester copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-22 US disclosed
US-3957732-A ALTERNATING COPOLYMERS HAVING FUNCTIONAL GROUP AND PROCESS FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069812-A1 Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents BIRC5, XIAP, BIRC2 CHRNB2 4033/4885CHRNB4 4268/4885CHRNA3 4498/4885
US-20220306791-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS LPO, SORD, GYS1 CHRNB2 4207/4885CHRNB4 4235/4885CHRNA3 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.