Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754162 | 0.88 | NR3C1 (0.56) | NR3C1NR3C2PGR | |
| SCHEMBL27748385 | 0.87 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL27774926 | 0.83 | NR3C1 (0.40) | NR3C1NR3C2PGR | |
| SCHEMBL27754133 | 0.83 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL28778649 | 0.81 | NR3C1 (0.40) | NR3C1NR3C2PGR | |
| SCHEMBL27769780 | 0.80 | GABRA1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL27757437 | 0.79 | NR3C1 (0.34) | NR3C1NR3C2PGR | |
| SCHEMBL27748398 | 0.78 | NR3C1 (0.50) | NR3C1NR3C2PGR | |
| SCHEMBL27769772 | 0.78 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL27769743 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553214-A | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-101528208-A | Compositions and methods for treating or preventing glaucoma or its progression | BAUSCH & LOMB (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101484187-A | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUCH & LOMB INC (US) | 2009-07-15 | — | — | CN | disclosed |