SCHEMBL27748723

SCHEMBL27748723

NS(=O)(=O)N1c2ccccc2Cc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
HPGD P15428 1/20 0.40
NOTUM Q6P988 1/20 0.38
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 3/20 0.38
MEN1 O00255 3/20 0.38
MAPT P10636 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 1/20 0.38
PABPC1 P11940 1/20 0.38
BLM P54132 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
NPSR1 Q6W5P4 1/20 0.36
SLC22A2 O15244 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
GABRA1 P14867 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3468967 0.86 HPGD (0.49) MAOAHPGDNOTUMALDH1A1CYP3A4
Sulfamide SCHEMBL29194997 0.72 MAOA (0.50) MAOAALDH1A1CYP3A4MEN1MAPT
SCHEMBL565581 0.72 HPGD (0.50) MAOAHPGDNOTUMKMT2AOPRM1
SCHEMBL7686001 0.71 MAPT (0.44) HPGDALDH1A1CYP3A4MEN1MAPT
SCHEMBL31375469 0.71 HPGD (0.53) MAOAHPGDNOTUMALDH1A1CYP3A4
SCHEMBL12320654 0.70 HPGD (0.42) MAOAHPGDNOTUMALDH1A1CYP3A4
SCHEMBL30885716 0.69 KMT2A (0.50) NOTUMALDH1A1MEN1KMT2ACA1
SCHEMBL87382 0.68 PARL (0.58) HPGDNOTUMALDH1A1CYP3A4MEN1
SCHEMBL651847 0.68 KMT2A (0.58) ALDH1A1MEN1MAPTKMT2ANPSR1
SCHEMBL29638283 0.68 KMT2A (0.58) ALDH1A1MEN1MAPTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101490536-B Nonseparation assay methods BECKMAN COULTER INC 2013-02-27 CN claimed
CN-102333885-A Non separation assays with selective signal inhibitors BECKMAN COULTER INC 2012-01-25 CN claimed
CN-101490536-A Nonseparation assay methods BECKMAN COULTER INC (US) 2009-07-22 CN claimed
CN-106680482-A Urine FXYD detection kit 上海良润生物医药科技有限公司 2017-05-17 CN disclosed
CN-106290899-A Test kit for detection by quantitative CST4 上海良润生物医药科技有限公司 2017-01-04 CN disclosed
CN-105785043-A Kit for quantitatively detecting AFP-L3% 上海良润生物医药科技有限公司 2016-07-20 CN disclosed