Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260818 | 0.73 | TDP1 (0.37) | KDM4EMAPTGMNNLMNATP53 | |
| SCHEMBL4646997 | 0.73 | HTT (0.34) | KDM4EMAPTGMNNLMNATP53 | |
| SCHEMBL31050548 | 0.73 | KDM4E (0.31) | KDM4EMAPTGMNNLMNATP53 | |
| Hydrochloric Acid SCHEMBL26638317 | 0.71 | TDP1 (0.35) | KDM4EMAPTGMNNLMNATP53 | |
| SCHEMBL10980109 | 0.65 | — | — | |
| SCHEMBL27639336 | 0.65 | LMNA (0.52) | KDM4EMAPTGMNNLMNATP53 | |
| SCHEMBL2935846 | 0.63 | TDP2 (0.32) | TDP1 | |
| SCHEMBL27791659 | 0.62 | KDM4E (0.30) | KDM4EMAPTGMNNLMNATP53 | |
| SCHEMBL3378330 | 0.62 | — | — | |
| SCHEMBL3174098 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495478-A | Imino-imidazo-pyridine derivatives with antithrombotic activity | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | disclosed |