Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | ESRRA | P11474 | 1/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819060 | 0.89 | CYP1A2 (0.60) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL2819059 | 0.89 | CYP1A2 (0.60) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL29538001 | 0.87 | CYP1A2 (0.78) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL8638081 | 0.87 | CYP1A2 (0.78) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL8638079 | 0.87 | CYP1A2 (0.78) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL9658958 | 0.84 | PKM (0.68) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL10435041 | 0.84 | CYP1A2 (0.70) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL5597271 | 0.84 | KMT2A (0.70) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL9658963 | 0.84 | PKM (0.68) | CYP1A2EGFRKDM4EPKMKMT2A | |
| SCHEMBL10435040 | 0.84 | CYP1A2 (0.70) | CYP1A2EGFRKDM4EPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495463-A | Seven-membered ring compound, production method thereof and pharmaceutical use thereof | ASUBIO PHARMA CO LTD (JP) | 2009-07-29 | — | — | CN | disclosed |