SCHEMBL5597271

SCHEMBL5597271

COc1cc(/C=C(\C#N)C(=O)O)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.70
MEN1 O00255 5/20 0.70
MAPT P10636 4/20 0.70
ALDH1A1 P00352 3/20 0.70
EGFR P00533 2/20 0.68
KLK7 P49862 2/20 0.66
CSNK2A1 P68400 3/20 0.65
KLK14 Q9P0G3 1/20 0.65
KLK5 Q9Y337 1/20 0.65
CYP1A2 P05177 1/20 0.62
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA9 Q16790 1/20 0.60
KDM4E B2RXH2 3/20 0.58
PLIN1 O60240 1/20 0.57
GAA P10253 1/20 0.57
ABHD5 Q8WTS1 1/20 0.57
PKM P14618 2/20 0.56
CISD1 Q9NZ45 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5328416 1.00 KMT2A (0.70) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL11801445 0.89 EGFR (0.68) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL11801440 0.89 EGFR (0.68) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL8638079 0.88 CYP1A2 (0.78) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL8638081 0.88 CYP1A2 (0.78) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL29538001 0.88 CYP1A2 (0.78) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL6874673 0.87 MEN1 (0.77) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL6874677 0.87 MEN1 (0.77) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL8608702 0.87 CYP1A2 (0.82) KMT2AMEN1MAPTALDH1A1EGFR
SCHEMBL8608700 0.87 CYP1A2 (0.82) KMT2AMEN1MAPTALDH1A1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007502314-A 2007-02-08 JP claimed
US-20070010579-A1 Copper salts of organic acids and use thereof as fungicides ISARGO S.P.A. (IT) 2007-01-11 US claimed
EP-1633190-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.p.A. (IT) 2006-03-15 EP claimed
WO-2004103074-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.P.A. (IT) 2004-12-02 WO claimed
EP-0403238-A2 Cosmetic composition UNILEVER PLC (GB) 1990-12-19 EP claimed
US-12030877-B2 Prostaglandin E synthase inhibitors and methods for utilizing the same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2024-07-09 US disclosed
US-20070010579-A1 Copper salts of organic acids and use thereof as fungicides ISARGO S.P.A. (IT) 2007-01-11 US disclosed
EP-1633190-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.p.A. (IT) 2006-03-15 EP disclosed
WO-2004103074-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.P.A. (IT) 2004-12-02 WO disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
EP-0580409-A2 Cosmetic composition containing DOPA derivatives UNILEVER PLC (GB) 1994-01-26 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
EP-0571198-A1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1993-11-24 EP disclosed
EP-0517371-A2 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1992-12-09 EP disclosed
EP-0490581-A1 Cosmetic composition UNILEVER PLC (GB) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010579-A1 Copper salts of organic acids and use thereof as fungicides AOC3, AOC2, AOC1 KMT2A 3220/4885MEN1 469/4885MAPT 679/4885
US-12030877-B2 Prostaglandin E synthase inhibitors and methods for utilizing the same PTGES, PTGS1, PTGES2 KMT2A 4205/4885MEN1 4764/4885MAPT 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.