Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093292 | 0.73 | FAAH (0.34) | ALDH1A1 | |
| SCHEMBL4196283 | 0.71 | ALDH1A1 (0.38) | SMYD3ALDH1A1SMN1; SMN2KDM4EPKM | |
| SCHEMBL4196695 | 0.70 | MAPT (0.41) | SMYD3ALDH1A1SMN1; SMN2KDM4EPKM | |
| Sulfuric Acid SCHEMBL29282607 | 0.67 | USP2 (0.31) | KDM4EPKM | |
| SCHEMBL25488971 | 0.67 | KDM4E (0.37) | SMYD3ALDH1A1SMN1; SMN2KDM4EPKM | |
| SCHEMBL29282609 | 0.66 | USP2 (0.33) | KDM4E | |
| SCHEMBL28688431 | 0.66 | KDM4E (0.39) | SMYD3ALDH1A1KDM4EPKM | |
| SCHEMBL12229004 | 0.65 | — | — | |
| SCHEMBL28788028 | 0.62 | KDM4E (0.39) | ALDH1A1SMN1; SMN2KDM4EPKM | |
| SCHEMBL30738556 | 0.62 | CA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500569-A | HIF hydroxylase inhibitors for treatment of anemia of cancer | FIBROGEN INC (US) | 2009-08-05 | — | — | CN | disclosed |
| CN-101490041-A | 2-heterocycloamino-4-imidazolylpyrimidines as agents for the inhibition of cell proliferation | ASTRAZENECA AB (SE) | 2009-07-22 | — | — | CN | disclosed |