Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748831 | 1.00 | TEAD1 (0.37) | TEAD1DDB1CRBNSPHK1PRMT5 | |
| SCHEMBL27770197 | 1.00 | TEAD1 (0.37) | TEAD1DDB1CRBNSPHK1PRMT5 | |
| SCHEMBL27748877 | 1.00 | TEAD1 (0.37) | TEAD1DDB1CRBNSPHK1PRMT5 | |
| SCHEMBL12371032 | 0.86 | NOTUM (0.38) | TEAD1NOTUMAKT1 | |
| SCHEMBL12371065 | 0.84 | SPHK1 (0.39) | TEAD1DDB1CRBNSPHK1 | |
| SCHEMBL12371060 | 0.82 | SPHK1 (0.42) | TEAD1SPHK1 | |
| SCHEMBL12371054 | 0.81 | SPHK1 (0.44) | TEAD1SPHK1 | |
| SCHEMBL2273765 | 0.80 | MAP1LC3B (0.39) | — | |
| SCHEMBL12370943 | 0.80 | MAP1LC3B (0.38) | NOTUM | |
| SCHEMBL2271030 | 0.80 | MAP1LC3B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490026-B | 2-oxetanone derivative and process for production thereof | CHISSO CORP | 2012-11-21 | — | — | CN | disclosed |
| CN-101490026-A | 2-oxetanone derivative and process for production thereof | CHISSO CORP (JP) | 2009-07-22 | — | — | CN | disclosed |