SCHEMBL27748976

SCHEMBL27748976

NCc1cc(Cl)cc(C(=O)NN)c1NC(=O)c1cc(Br)cn1-c1ccncc1Cl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
F10 P00742 1/20 0.32
CAPN1 P07384 1/20 0.31
GALR3 O60755 1/20 0.31
NR2F2 P24468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951524 0.88 F10 (0.34) ALDH1A1F10CAPN1KDM4EMAPT
SCHEMBL27727887 0.84 GRM5 (0.35) ALDH1A1F10KDM4EGRM5
SCHEMBL27748973 0.84
SCHEMBL28801562 0.82 ALDH1A1 (0.36) ALDH1A1F10KDM4EMAPT
SCHEMBL27727947 0.82 PSD (0.34) ALDH1A1F10MAPTGRM5
SCHEMBL12528817 0.80 NUDT1 (0.34) ALDH1A1F10CAPN1MAPT
SCHEMBL12911771 0.78 F10 (0.33) F10CAPN1
SCHEMBL12559257 0.77 ALDH1A1 (0.37) ALDH1A1F10CAPN1KDM4EMAPT
SCHEMBL950524 0.75 PDE4A (0.34) ALDH1A1F10KDM4E
SCHEMBL5332617 0.73 MAPT (0.37) ALDH1A1F10KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed