SCHEMBL277490

SCHEMBL277490

CCC(=CC=C(C)C(=O)O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.40
FFAR3 O14843 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
AKR1C3 P42330 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022079 1.00 PTGS1 (0.40) PTGS1FFAR3ALDH1A1TDP1GRIK1
SCHEMBL11238027 0.92 PTGS1 (0.35) PTGS1
Acrylic Acid SCHEMBL10460319 0.90 LMNA (0.39) PTGS1ALDH1A1GRIK1GRIK2TSHR
SCHEMBL158310 0.87 FFAR3 (0.44) FFAR3ALDH1A1TDP1GRIK1GRIK2
SCHEMBL16674848 0.83 TDP1 (0.36) FFAR3ALDH1A1TDP1GRIK1GRIK2
SCHEMBL9500702 0.82 ALDH1A1 (0.48) PTGS1ALDH1A1TSHR
SCHEMBL28151486 0.81 PTGS1 (0.34) PTGS1ALDH1A1
Styrene SCHEMBL10808703 0.80 AKR1C3 (0.46) ALDH1A1TDP1GRIK1AKR1C3KDM4E
SCHEMBL3791596 0.79 PTGS1 (0.55) PTGS1FFAR3ALDH1A1TDP1AKR1C3
SCHEMBL1900173 0.79 PTGS1 (0.55) PTGS1FFAR3ALDH1A1TDP1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2680823-B1 BINDER POWDERS NANO4M LTD (GB) 2024-05-15 EP claimed
US-11311490-B2 Oral preparation with controlled release ADD ADVANCED DRUG DELIVERY TECHNOLOGIES LTD. (CH) 2022-04-26 US claimed
EP-2453880-B1 SEPARATING LAYERS FOR PHARMACEUTICAL PREPARATIONS TO PREVENT INTERACTIONS BETWEEN MEDICINAL DRUGS AND PHARMACEUTICAL-TECHNOLOGICAL ADJUVANTS ADD TECH LTD (CH) 2019-02-13 EP claimed
EP-2701689-B1 PHARMACEUTICAL COMPOSITIONS OF RALTEGRAVIR, METHODS OF PREPARATION AND USE THEREOF HETERO RESEARCH FOUNDATION (IN) 2017-08-23 EP claimed
US-9492545-B2 Compositions of statins and omega-3 fatty acids OMTHERA PHARMACEUTICALS INC. (US) 2016-11-15 US claimed
US-20150104504-A1 COMPOSITIONS OF STATINS AND OMEGA-3 FATTY ACIDS OMTHERA PHARMACEUTICALS, INC. 2015-04-16 US claimed
EP-2846779-A1 COMPOSITIONS OF STATINS AND OMEGA-3 FATTY ACIDS Omthera Pharmaceuticals Inc. (US) 2015-03-18 EP claimed
WO-2013169797-A1 COMPOSITIONS OF STATINS AND OMEGA-3 FATTY ACIDS OMTHERA PHARMACEUTICALS, INC. (US) 2013-11-14 WO claimed
US-20130295173-A1 COMPOSITIONS OF STATINS AND OMEGA-3 FATTY ACIDS OMTHERA PHARMACEUTICALS, INC. 2013-11-07 US claimed
EP-1915137-B1 ORAL PREPARATION WITH CONTROLLED RELEASE ADD ADVANCED DRUG DELIVERY TECHNOLOGIES LTD (CH) 2013-08-07 EP claimed
EP-2104692-B1 METHACRYLATE RESIN WITH EXCELLENT DISCOLORATION-RESISTANCE AND TRANSPARENCY AND METHOD FOR PREPARING THE SAME CHEIL IND INC (KR) 2012-08-08 EP claimed
US-8030252-B2 Drilling or fructuring fluid containing an oleaginous fluid ( diesel oil, cude oil, paraffin oil, olefin etc.) a fluid ( water, fresh or brine, glycerol, polyetheramine) that is partially immiscible with the oleaginous fluid, and emulsion facilitating particles; treating the subterranean formation HALLIBURTON ENERGY SERVICES INC. (US) 2011-10-04 US claimed
US-20100151017-A1 Oral Preparation With Controlled Release ADD ADVANCED DRUG DELIVERY TECHNOLOGIES LTD. (CH) 2010-06-17 US claimed
US-20090311319-A1 Oral Preparation With Controlled Release ADD ADVANCED DRUG DELIVERY TECHNOLOGIES LTD. (CH) 2009-12-17 US claimed
EP-1499300-B1 PHARMACEUTICAL FORMULATIONS WITH IMPROVED BIOAVAILABILITY SUPERNUS PHARMACEUTICALS INC (US) 2009-03-18 EP claimed
EP-1985289-A2 Rapidly soluble film covering based on polyvinylalcohol-polyether graft copolymers combined with components containing hydroxyl, amide or ester functions BASF SE (DE) 2008-10-29 EP claimed
US-20080154008-A1 Methacrylate Resin with Excellent Discoloration-Resistance and Transparency and Method for Preparing the Same CHEIL INDUSTRIES INC. (KR) 2008-06-26 US claimed
EP-1478351-A1 RAPIDLY SOLUBLE FILM COVERING BASED ON POLYVINYLALCOHOL-POLYETHER GRAFT COPOLYMERS COMBINED WITH COMPONENTS CONTAINING HYDROXYL, AMIDE, OR ESTER FUNCTIONS BASF AKTIENGESELLSCHAFT (DE) 2004-11-24 EP claimed
EP-0879404-B1 TIME-TEMPERATURE INTEGRATING INDICATOR DEVICE MINNESOTA MINING & MFG (US) 2004-08-04 EP claimed
WO-2003070224-A1 RAPIDLY SOLUBLE FILM COVERING BASED ON POLYVINYLALCOHOL-POLYETHER GRAFT COPOLYMERS COMBINED WITH COMPONENTS CONTAINING HYDROXYL, AMIDE, OR ESTER FUNCTIONS BASF AKTIENGESELLSCHAFT (DE) 2003-08-28 WO claimed