Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571764 | 0.78 | ALDH1A1 (0.50) | CA1CA2CA9CA12CA6 | |
| SCHEMBL27874923 | 0.78 | F2 (0.47) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6680428 | 0.74 | CA1 (0.70) | CA1CA2CA9CA12CA4 | |
| SCHEMBL15212526 | 0.73 | CA1 (0.57) | CA1CA2CA9CA12CA4 | |
| SCHEMBL506866 | 0.73 | PSIP1 (0.59) | CA1CA2CA9CA12CA4 | |
| Hydrochloric Acid SCHEMBL3956091 | 0.72 | CA1 (0.71) | CA1CA2CA9CA12CA4 | |
| Mafenide SCHEMBL27599824 | 0.72 | KDM4E (0.82) | CA1CA2CA9CA12CA4 | |
| SCHEMBL27653382 | 0.70 | CA1 (0.53) | CA1CA2CA9CA12CA4 | |
| SCHEMBL27773980 | 0.70 | ALDH1A1 (0.65) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3256372 | 0.70 | SLC1A3 (0.49) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |