SCHEMBL2774975

SCHEMBL2774975

N#Cc1nc(C(F)(F)F)c(C(F)(F)F)nc1C#N

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
NCOA1 Q15788 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
MAPT P10636 1/20 0.32
XBP1 P17861 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14316195 0.87 MAPT (0.36) HTTMAPTXBP1
SCHEMBL14316186 0.87 MAPT (0.36) HTTMAPTXBP1
SCHEMBL17447244 0.80 MAPT (0.35) HTTMAPTXBP1
SCHEMBL17447301 0.80 MAPT (0.35) HTTMAPTXBP1
SCHEMBL17447215 0.80 MAPT (0.33) HTTMAPTXBP1
SCHEMBL17447245 0.77 MAPT (0.36) HTTMAPTXBP1
SCHEMBL27476691 0.74 HTT (0.35) HTTLMNAPOLBNCOA1SMN1; SMN2
SCHEMBL12343927 0.74 MBOAT4 (0.32) HTTLMNAPOLBNCOA1SMN1; SMN2
SCHEMBL14316175 0.71 HTT (0.36) HTTLMNAPOLBNCOA1SMN1; SMN2
SCHEMBL16598242 0.71 ALDH1A1 (0.40) POLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7695850-B2 using a cobalt tetrapyrazinoporphyrazine derivative as a stable reduction catalyst; air cells, fuel cells, electrochemical sensors and electrochemical devices; high potential; oxidation resistance PANASONIC CORPORATION (JP) 2010-04-13 US disclosed
US-7695850-B2 using a cobalt tetrapyrazinoporphyrazine derivative as a stable reduction catalyst; air cells, fuel cells, electrochemical sensors and electrochemical devices; high potential; oxidation resistance PANASONIC CORPORATION (JP) 2010-04-13 US disclosed
US-7695850-B2 using a cobalt tetrapyrazinoporphyrazine derivative as a stable reduction catalyst; air cells, fuel cells, electrochemical sensors and electrochemical devices; high potential; oxidation resistance PANASONIC CORPORATION (JP) 2010-04-13 US disclosed
US-20070243449-A1 using a cobalt tetrapyrazinoporphyrazine derivative as a stable reduction catalyst; air cells, fuel cells, electrochemical sensors and electrochemical devices; high potential; oxidation resistance PANASONIC CORPORATION (JP) 2007-10-18 US disclosed
US-20070243449-A1 using a cobalt tetrapyrazinoporphyrazine derivative as a stable reduction catalyst; air cells, fuel cells, electrochemical sensors and electrochemical devices; high potential; oxidation resistance PANASONIC CORPORATION (JP) 2007-10-18 US disclosed
US-20070243449-A1 using a cobalt tetrapyrazinoporphyrazine derivative as a stable reduction catalyst; air cells, fuel cells, electrochemical sensors and electrochemical devices; high potential; oxidation resistance PANASONIC CORPORATION (JP) 2007-10-18 US disclosed