Imidazole

Imidazole

SCHEMBL27749802

c1c[nH]cn1.c1cnc2cccnc2c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
FKBP5 Q13451 1/20 0.56
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
NR4A2 P43354 2/20 0.35
ATAD2 Q6PL18 1/20 0.34
POLB P06746 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
AXL P30530 1/20 0.33
NUDT1 P36639 1/20 0.33
CYP19A1 P11511 1/20 0.33
TBXAS1 P24557 1/20 0.33
CYP3A4 P08684 1/20 0.32
HTT P42858 3/20 0.31
MEN1 O00255 2/20 0.31
CASP1 P29466 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 2/20 0.31
HSP90AA1 P07900 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoxaline SCHEMBL83382 0.91 ALDH1A1 (0.56) ALDH1A1FKBP5MAPTKDM4EPOLB
Quinoline SCHEMBL27877830 0.88 ALDH1A1 (0.63) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL2029469 0.88 ALDH1A1 (0.63) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL27685815 0.88 ALDH1A1 (0.63) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL27277627 0.88 ALDH1A1 (0.63) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL27929361 0.87 ALDH1A1 (0.61) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL28126307 0.87 ALDH1A1 (0.61) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL27750058 0.87 ALDH1A1 (0.61) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL28232319 0.87 ALDH1A1 (0.61) ALDH1A1FKBP5MAPTKDM4ENR4A2
Quinoline SCHEMBL27268450 0.87 ALDH1A1 (0.61) ALDH1A1FKBP5MAPTKDM4ENR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858530-A Optoelectronic device and method for producing the same TCL科技集团股份有限公司 2024-04-09 CN claimed
CN-117858530-A Optoelectronic device and method for producing the same TCL科技集团股份有限公司 2024-04-09 CN disclosed
CN-113735780-B Benzo five-membered heterocyclic derivative and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2024-04-05 CN disclosed
CN-113816921-B Heterocyclic compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2023-12-19 CN disclosed
CN-115322197-B Imidazonaphthyridine compound with affinity with Tau protein, and preparation method and application thereof 北京师范大学 2023-09-29 CN disclosed
CN-115322197-A Imidazonaphthyridine compound with affinity to Tau protein and preparation method and application thereof 北京师范大学 2022-11-11 CN disclosed
CN-107109229-A Device for regulating the passage of energy 默克专利股份有限公司 2017-08-29 CN disclosed
CN-102006777-A Herbicidal coumpounds SYNGENTA LTD 2011-04-06 CN disclosed
CN-101492446-A Novel pyridine-imidazole derivative SHANDONG XUANZHU PHARM TECH CO (CN) 2009-07-29 CN disclosed