Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 11/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879923 | 0.83 | HPGDS (0.62) | HPGDSPOLBPRMT5MAPTSMN1; SMN2 | |
| SCHEMBL27772579 | 0.82 | SMO (0.39) | HPGDSL3MBTL1RIPK1PRMT5SMN1; SMN2 | |
| SCHEMBL27812236 | 0.78 | USP30 (0.51) | HPGDS | |
| SCHEMBL16054078 | 0.77 | HPGDS (0.45) | HPGDSL3MBTL1RIPK1 | |
| SCHEMBL16054075 | 0.77 | HPGDS (0.45) | HPGDSL3MBTL1RIPK1 | |
| SCHEMBL27488566 | 0.76 | RIPK1 (0.51) | L3MBTL1RIPK1 | |
| SCHEMBL19427933 | 0.75 | NPC1 (0.46) | HPGDSHTR2BPOLBL3MBTL1MAPT | |
| SCHEMBL27892543 | 0.74 | HTR2B (0.42) | HPGDSHTR2B | |
| SCHEMBL4956602 | 0.74 | TSHR (0.47) | HPGDSL3MBTL1RIPK1MAPT | |
| SCHEMBL27812289 | 0.74 | HTT (0.56) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511815-A | New pyridine analogues | ASTRAZENECA AB (SE) | 2009-08-19 | — | — | CN | disclosed |