Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941345 | 0.84 | HPGDS (0.50) | HPGDSPOLBL3MBTL1HTR2CHTR2A | |
| Tert-Butyl Formate SCHEMBL27772583 | 0.81 | GABRA1 (0.41) | HTR2CGABRA1GABRB2KHKGABRG2 | |
| Tert-Butyl Formate SCHEMBL27812239 | 0.78 | USP30 (0.44) | HPGDS | |
| Tert-Butyl Formate SCHEMBL27488567 | 0.76 | SLC18A3 (0.62) | HTR2CSLC18A3SIGMAR1HTR6 | |
| SCHEMBL19385306 | 0.76 | HPGDS (0.52) | HPGDSHTR2CHTR2AKCNH2GABRA1 | |
| SCHEMBL19427933 | 0.76 | NPC1 (0.46) | HPGDSPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL2755241 | 0.73 | MEN1 (0.51) | HTR2CHTR2ANPC1RAB9APLAT | |
| Tert-Butyl Formate SCHEMBL27812290 | 0.73 | KMT2A (0.58) | POLB | |
| SCHEMBL18845580 | 0.73 | ADORA1 (0.46) | POLBL3MBTL1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL29562329 | 0.72 | HPGDS (0.44) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511815-A | New pyridine analogues | ASTRAZENECA AB (SE) | 2009-08-19 | — | — | CN | disclosed |