Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.58 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.58 |
| ▸ | MEP1B | Q16820 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765921 | 0.86 | FOLH1 (0.61) | FOLH1ANPEPENPEPMEP1B | |
| SCHEMBL8375490 | 0.84 | FOLH1 (0.59) | FOLH1ANPEPENPEPMEP1B | |
| SCHEMBL1397444 | 0.84 | ANPEP (0.69) | FOLH1ANPEPENPEP | |
| SCHEMBL9622159 | 0.84 | ANPEP (0.69) | FOLH1ANPEPENPEP | |
| SCHEMBL14478232 | 0.84 | ANPEP (0.69) | FOLH1ANPEPENPEP | |
| SCHEMBL27785276 | 0.83 | FOLH1 (0.58) | FOLH1ANPEPENPEP | |
| SCHEMBL28435225 | 0.83 | ANPEP (0.67) | FOLH1ANPEPENPEP | |
| SCHEMBL9209594 | 0.83 | FOLH1 (0.62) | FOLH1ANPEPENPEPMEP1B | |
| SCHEMBL27751364 | 0.83 | FOLH1 (0.58) | FOLH1ANPEPENPEPMEP1B | |
| Hydrochloric Acid SCHEMBL27656347 | 0.83 | ANPEP (0.67) | FOLH1ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374815-B | Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (HIF) | FIBROGEN INC | 2013-07-17 | — | — | CN | disclosed |
| CN-102351791-A | Cyanoisoquinoline compounds capable of making hypoxia inducible factor (HIF) stable | FIBROGEN INC | 2012-02-15 | — | — | CN | disclosed |
| CN-101374815-A | Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (HIF) | FIBROGEN INC (US) | 2009-02-25 | — | — | CN | disclosed |