SCHEMBL1397444

SCHEMBL1397444

C[C@@H](N)Cc1cccc(C(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ANPEP P15144 1/20 0.69
▸ ENPEP Q07075 1/20 0.69
▸ FOLH1 Q04609 8/20 0.59
▸ SLC6A2 P23975 2/20 0.57
▸ TAAR1 Q96RJ0 2/20 0.57
▸ MAOA P21397 1/20 0.57
▸ SLC6A4 P31645 1/20 0.57
▸ SLC6A3 Q01959 1/20 0.57
▸ SIGMAR1 Q99720 1/20 0.57
▸ CYP2A6 P11509 1/20 0.57
▸ ADORA2A P29274 1/20 0.57
▸ ADORA1 P30542 1/20 0.57
▸ SLC7A5 Q01650 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622159 1.00 ANPEP (0.69) ANPEPENPEPFOLH1SLC6A2TAAR1
SCHEMBL14478232 1.00 ANPEP (0.69) ANPEPENPEPFOLH1SLC6A2TAAR1
Hydrochloric Acid SCHEMBL27656347 0.98 ANPEP (0.67) ANPEPENPEPFOLH1SLC6A2TAAR1
Isophthalic Acid SCHEMBL28055755 0.91 SLC6A2 (0.66) ANPEPENPEPFOLH1SLC6A2TAAR1
Trifluoroacetamide SCHEMBL9181331 0.89 ANPEP (0.57) ANPEPENPEPFOLH1SLC6A2TAAR1
SCHEMBL765921 0.87 FOLH1 (0.61) ANPEPENPEPFOLH1
Amphetamine SCHEMBL21464672 0.87 TAAR1 (0.70) ANPEPENPEPSLC6A2TAAR1MAOA
Amphetamine SCHEMBL29185448 0.87 TAAR1 (0.70) ANPEPENPEPSLC6A2TAAR1MAOA
Glutamic Acid SCHEMBL1033856 0.86 FOLH1 (0.53) ANPEPENPEPFOLH1SLC7A5
SCHEMBL6105481 0.86 ANPEP (0.55) ANPEPENPEPSLC6A2TAAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332223-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2025-10-30 — — US claimed
US-12377135-B2 GHRH antagonists for use in a method of treating sarcoidosis UNIVERSITY OF MIAMI (US) 2025-08-05 — — US claimed
EP-4331674-A2 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2024-03-06 — — EP claimed
EP-3999095-B1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2023-09-13 — — EP claimed
EP-3999095-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2022-05-25 — — EP claimed
US-20220143149-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2022-05-12 — — US claimed
WO-2021011874-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIVERSITY OF MIAMI (US) 2021-01-21 — — WO claimed
US-20200276273-A1 METHOD FOR TREATING MYELOID LEUKEMIA THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2020-09-03 — — US claimed
WO-2019060601-A1 METHOD FOR TREATING MYELOID LEUKEMIA UNIVERSITY OF MIAMI (US) 2019-03-28 — — WO claimed
CN-102977212-A Compositions comprising anti-IGF-1r antibodies and methods for their production AMGEN INC 2013-03-20 — — CN claimed
US-20250332223-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2025-10-30 — — US disclosed
US-12377135-B2 GHRH antagonists for use in a method of treating sarcoidosis UNIVERSITY OF MIAMI (US) 2025-08-05 — — US disclosed
EP-4331674-A2 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2024-03-06 — — EP disclosed
EP-3999095-B1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2023-09-13 — — EP disclosed
EP-3999095-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2022-05-25 — — EP disclosed
US-4369037-A Hair treatment cosmetics containing cationic keratin derivatives KAO SOAP CO., LTD. (JP) 1983-01-18 — — US disclosed
US-4364926-A INHIBITORS OF TRANSFERASES; ALKALI RESISTANCE; HEAT RESISTANCE; DENTIFRICES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1982-12-21 — — US disclosed
US-4314999-A N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity PROTER S.P.A. (IT) 1982-02-09 — — US disclosed
US-4294856-A Process for manufacture of artificial milk replacer for raising infant pigs and other infant animals Tokai Regional Fisheries Research Laboratory (JP) 1981-10-13 — — US disclosed
US-3948875-A Process for the preparation of epidermal growth factor and new derivative using cross-linked polyacrylamide gel at a pH of 1-3 COHEN STANLEY 1976-04-06 — — US disclosed
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