Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27753138

COCCOC(=O)c1c(F)c(F)c(F)c(F)c1F.N

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.51
RECQL P46063 2/20 0.49
TSHR P16473 2/20 0.48
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
ALDH1A1 P00352 3/20 0.43
GAA P10253 3/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 2/20 0.40
MAPK1 P28482 1/20 0.40
MAPT P10636 2/20 0.38
ABCB11 O95342 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADRA2B P18089 1/20 0.37
OPRD1 P41143 1/20 0.37
SCN5A Q14524 1/20 0.37
TP53 P04637 2/20 0.37
NPSR1 Q6W5P4 2/20 0.36
HTT P42858 2/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4582621 0.87 ESR1 (0.57) ESR1RECQLTSHRCA1CA2
Ethylene SCHEMBL4583799 0.83 ESR1 (0.53) ESR1RECQLTSHRCA1CA2
SCHEMBL19795495 0.79 ESR1 (0.65) ESR1RECQLTSHRCA1CA2
SCHEMBL17367967 0.79 ESR1 (0.63) ESR1RECQLTSHRCA1CA2
SCHEMBL13291852 0.79 ESR1 (0.63) ESR1RECQLTSHRCA1CA2
SCHEMBL8567444 0.77 ESR1 (0.45) ESR1RECQLTSHRCA1CA2
SCHEMBL12972082 0.77 ESR1 (0.49) ESR1RECQLTSHRCA1CA2
SCHEMBL522911 0.77 ESR1 (0.67) ESR1TSHRCA1CA2ALDH1A1
SCHEMBL27554367 0.77 ESR1 (0.52) ESR1RECQLTSHRCA1CA2
SCHEMBL17367633 0.76 ESR1 (0.83) ESR1RECQLTSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101316810-A Ionic liquids BIONIQS LTD (GB) 2008-12-03 CN disclosed