Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582621 | 0.95 | ESR1 (0.57) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL17367967 | 0.86 | ESR1 (0.63) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL13291852 | 0.86 | ESR1 (0.63) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL8567444 | 0.84 | ESR1 (0.45) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL27554367 | 0.84 | ESR1 (0.52) | ESR1CA1CA2RECQLTSHR | |
| Ammonia Solution, Strong SCHEMBL27753138 | 0.83 | ESR1 (0.51) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL28109003 | 0.82 | ESR1 (0.50) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL19795495 | 0.82 | ESR1 (0.65) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL2833921 | 0.81 | ESR1 (0.46) | ESR1CA1CA2RECQLTSHR | |
| SCHEMBL13250952 | 0.80 | ESR1 (0.58) | ESR1CA1CA2RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530269-B2 | Manufacture of a polymer device | CAMBRIDGE ENTERPRISE LTD (GB) | 2013-09-10 | — | — | US | disclosed |
| EP-1631995-B1 | MANUFACTURE OF A POLYMER DEVICE | CAMBRIDGE ENTPR LTD (GB) | 2008-07-16 | — | — | EP | disclosed |
| US-20070172978-A1 | Manufacture of a polymer device | CAMBRIDGE UNIVERSITY TECHNICAL SERVICE LIMITED (GB) | 2007-07-26 | — | — | US | disclosed |