SCHEMBL2775346

SCHEMBL2775346

CC(C(=O)OC1CC(C)(C)N(CCOC(=O)CCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(C)(C)C1)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
GAA P10253 5/20 0.36
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
MAOB P27338 3/20 0.34
MAOA P21397 2/20 0.34
HMGCR P04035 2/20 0.33
ACHE P22303 1/20 0.33
ALOX5 P09917 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1A O00555 1/20 0.30
CACNA2D1 P54289 1/20 0.30
CACNB1 Q02641 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192202 0.93 KMT2A (0.38) KMT2AMEN1GAAPKMHTT
SCHEMBL5415492 0.91 GAA (0.34) KMT2AMEN1GAAPKMHTT
SCHEMBL206978 0.90 KMT2A (0.43) KMT2AMEN1GAAPKMHTT
SCHEMBL2958675 0.84 ALOX5 (0.44) KMT2AMEN1GAAPKMHTT
SCHEMBL2998267 0.84 APP (0.40) KMT2AMEN1GAAPKMHTT
SCHEMBL17866245 0.83 KMT2A (0.38) KMT2AMEN1GAAPKMHTT
SCHEMBL9180631 0.83 KMT2A (0.42) KMT2AMEN1GAAPKMHTT
SCHEMBL4183573 0.83 KMT2A (0.42) KMT2AMEN1GAAPKMHTT
SCHEMBL1873143 0.83 KMT2A (0.34) KMT2AMEN1GAAPKMHTT
SCHEMBL679220 0.82 KMT2A (0.39) KMT2AMEN1GAAPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371616-B2 Laminate and production method thereof KONICA MINOLTA HOLDINGS, INC. (JP) 2016-06-21 US disclosed
US-20100173146-A1 LAMINATE AND PRODUCTION METHOD THEREOF KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-08 US disclosed