Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14381152 | 1.00 | GAA (0.54) | GAAKMT2AHPGDMEN1SLC1A1 | |
| SCHEMBL1768744 | 0.88 | SLC1A1 (0.67) | GAAKMT2AHPGDMEN1SLC1A1 | |
| SCHEMBL1768747 | 0.88 | SLC1A1 (0.67) | GAAKMT2AHPGDMEN1SLC1A1 | |
| SCHEMBL14381160 | 0.84 | SLC1A1 (0.66) | GAAKMT2AHPGDMEN1SLC1A1 | |
| SCHEMBL28279974 | 0.83 | GAA (0.58) | GAAKMT2AHPGDMEN1SLC1A1 | |
| SCHEMBL6432230 | 0.82 | HPGD (0.60) | GAAKMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL4788083 | 0.82 | HPGD (0.60) | GAAKMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL15514213 | 0.81 | KMT2A (0.63) | GAAKMT2AHPGDMEN1MCL1 | |
| SCHEMBL14005782 | 0.80 | ALDH1A1 (0.53) | GAAKMT2AHPGDMEN1SLC1A1 | |
| SCHEMBL22636418 | 0.80 | GAA (0.54) | GAAKMT2AHPGDMEN1SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | claimed |
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | disclosed |