Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361032 | 0.75 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL2361034 | 0.75 | PPARD (0.38) | DGAT1 | |
| SCHEMBL27755242 | 0.73 | FFAR3 (0.36) | — | |
| SCHEMBL28604147 | 0.71 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL28604148 | 0.71 | — | — | |
| SCHEMBL8919404 | 0.70 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL9936531 | 0.66 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL23009448 | 0.66 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL21295120 | 0.65 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL16485863 | 0.64 | GAA (0.48) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528713-B | Pyridazine derivatives as inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 | HOFFMANN LA ROCHE | 2013-05-22 | — | — | CN | disclosed |
| CN-101528713-A | Pyridazine derivatives as inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 | HOFFMANN LA ROCHE (CH) | 2009-09-09 | — | — | CN | disclosed |